In this report examining the U.S. chemical industry, James Heintz shows that a shift to the production of chemicals that are safer for workers, the environment and human health can create jobs and new markets. The chemical industry has shed 300,000 jobs since 1992, and has under-invested in research and development. These job losses—and their continuation under the status quo—are not inevitable. The study finds that shifting the industry towards greater disclosure, appropriate regulation (such as reform of the 1976 Toxic Substances Control Act), and long-run sustainability would encourage innovation, support competitiveness, and renew manufacturing jobs.